Childhood
- Full name - Pearl Comfort Sydenstricker also known by her Chinese name Sai Zhenzhu
- Born in Hillsboro, West Virginia, United States on June 16, 1892
- Was the fourth of seven children from Absalam and Caroline Sydenstricker
- Parents were Presbyterian missionaries in China
- Attended boarding school in Shanghai, China from 1907 to 1909 because of the Anti-Foreign Boxer Rebellion of 1900